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Further molecular detail of the receptor downregulation mechanism, determination of growth factor signalling thresholds required to instigate ERα loss, and the impact of hyperactivation of additional signalling cascades (e.g. phosphatidylinositol 3' kinase [ 6]) is now required.
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At this time, national guidance was in place across England and Wales requiring hospitals to instigate a series of actions relating to the safe intrathecal administration of chemotherapy, and to prevent the administration of vinca alkaloids intended for intravenous administration via the incorrect route.
In lieu of domestic action, sustained international pressure on Naypyidaw - something that an influential country such as the UK could help to instigate - is surely required to prevent a future catastrophe from taking place.
A virtual sex crime might elicit a very different response if, instead of pressing a button to instigate it, you were required to mimic its pelvic thrusts and parries — even if, as in Nabokov's work, it was included to illustrate or illuminate, not titillate.
To instigate bone formation, cells need to adhere and proliferate.
Perhaps destination countries find it cheaper to continue to recruit internationally rather than to instigate the change – to policy and practice – required to retain migrant nurses in post [ 17].
In vitro and in vivo studies demonstrated that gemcitabine required PUMA transcription to instigate an apoptotic programme.
We assessed experts' preferred methods of detecting and treating depression in palliative care, but we did not address the decisions and actions required after detection to instigate appropriate and effective intervention.
A program of work was instigated to determine the cause of the failure, and its consequences, i.e. the pressures reached and what work was required to ensure that the unit was fit for reuse.
We should instigate a real, hard copy Poetry Licence, like the pen licence handed out in third grade when you graduate from using a pencil, or the driver's licence that's required to get behind a wheel.
In a music world where streaming services often require the user to instigate the conversation, Beats 1's aim is to bring the unknown of radio into people's phones.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com