This analysis, however, also requires the validation of the synthetic waveforms themselves due to the presence of an oceanic water layer and thick sediments that can cause large effects on the excitations and propagations of the seismic waves, in the source area.
Such therapy guidance requires the validation of the predictive capability of the biomarker.
Such efforts would require the validation of a suitable model of human metastatic melanoma, lack of which represents a significant barrier to translational research in metastatic disease.
Background noise may be the source of false positives, which will require the validation of cases, within patients detected by the automated clinical decision support system, by infection control practitioners before alerting health care providers.
There is a growing movement to require the validation of all cell lines used in sponsored research [ 3], and some journals and repositories have heeded the call [ 1, 2].
A key step necessary to begin to resolve these discrepancies between theory and empirical observations requires the validation of fitness consequences of variation at specific loci or pathways in the field (Turelli and Barton, 2004; Fournier-Level et al., 2011; Hancock et al., 2011).
We discuss fundamental assumptions required for the validation of dietary questionnaire assessments, using latent variable models.
Until about the 8th century, the signature of the Merovingian ruler or his delegate was also required for the validation of public documents, but thereafter the seal alone, together with the recognition by a high chancery official, was held sufficient, the king's signature dwindling into a monogram or mere stroke (the "stroke of execution").
The datasets used to generate the results presented here contain some patient-level information; for reasons of confidentiality we have presented only the relevant aggregate data required for the validation of the PRO.
The slope in the relative efficiency plots for SNCA and the reference genes were >0.1, showing a standard value required for the validation of the relative quantitative method (Figure S1).
