required substitution

USAGE SUMMARY

The phrase "required substitution" is correct and usable in written English.
It can be used in contexts where a change or replacement is necessary, such as in technical, academic, or instructional writing. Example: "In order to complete the experiment, a required substitution of the chemical compound must be made."

✓ Grammatically correct

Science

News & Media

Human-verified examples from authoritative sources

Exact Expressions

7 human-written examples

For example, if there is a hypothesis for the age of a particular node in the phylogeny of a group of taxa with an nrITS dataset, one could calculate the required substitution rate to fit that age to the node and then compare the required rate to the distribution of rates presented here.

BMC Evolutionary Biology

The United States Court of Appeals for the Ninth Circuit ruled that the district judge handling the case was required to examine the facts and decide "whether the interests of justice required substitution of counsel" when the inmate, Kenneth Clair, complained that his lawyer was not pursuing important evidence in his federal habeas corpus appeal.

The New York Times

This study assessed individual SNP genotyping precision using the Ion PGM™, the forensic sensitivity of the multiplex using dilution series, degraded DNA plus simple mixtures, and the ancestry differentiation power of the final panel design, which required substitution of three original ancestry-informative SNPs with alternatives.

Forensic Science International: Genetics

Children stopped using MEMS caps when tuberculosis treatment required substitution of efavirenz for nevirapine and hence separate drugs rather than the FDC tablets.

Plosone

In some participants, severe pain throughout the range of motion required substitution of isometric exercises of particular exercises intermittently during the 6 month of training.

BMC Geriatrics

Out of the 95 weeks' diaries of MPSS data, six days (1%) contained too little information to be included, and 15 other items were missing and required substitution (total missing data = 2.0%).

BMC Complementary and Alternative Medicine

Human-verified similar examples from authoritative sources

Similar Expressions

53 human-written examples

One-, two- or multiple-point mutations are possible by specification of residues to be mutated and the required substitutions.

Bioinformatics

In other words, let's say evolution of wt PTE into AE required substitutions Z1z and Y2y (i.e. ZY at positions 1/2 = phenotype 1 and zy at positions 1/2 = phenotype 2) but that a third mutation, say X3x occurred at position 3.

eLife

In other words, let's say evolution of wtPTE into AE required substitutions Z1z and Y2y (i.e. ZY at positions 1/2 = phenotype 1 and zy at positions 1/2 = phenotype 2) but that a third mutation, say X3x occurred at position 3.

eLife

The Dane injured himself badly enough in the process to require substitution.

The Guardian - Sport

These units aim at receiving patients who need close monitoring, or present a risk of a potential organ failure without requiring substitution.

Annals of Intensive Care

Expert writing Tips

Best practice

When using "required substitution", ensure the context clearly explains why the substitution is necessary and what is being replaced.

Common error

Avoid using "required substitution" in casual conversation or informal writing; simpler terms like "needed replacement" or "had to change" may be more appropriate.

Linguistic Context

The phrase "required substitution" functions as a noun phrase, where "required" acts as an adjective modifying the noun "substitution". It indicates that a replacement is not merely optional, but necessary under given circumstances. As noted by Ludwig AI, the phrase is correct and usable.

Expression frequency: Uncommon

Frequent in

Science

71%

News & Media

21%

Wiki

7%

Less common in

Formal & Business

0%

Encyclopedias

0%

Reference

0%

Ludwig's WRAP-UP

In summary, "required substitution" is a grammatically correct noun phrase indicating a necessary replacement. Ludwig AI confirms its usability, particularly in technical and formal contexts. While its frequency is uncommon, its precise meaning makes it valuable in specific situations. Simpler alternatives exist for informal settings. The phrase is predominantly used in science and news & media sources. Always ensure clarity when using "required substitution", specifying why the change is necessary. A "required substitution" signifies more than a simple change; it's a necessary alteration.

More alternative expressions

Phrases that express similar concepts, ordered by semantic similarity:

necessary replacement

Focuses on the replacement being essential, similar to the original phrase.

mandatory substitution

Emphasizes the obligatory nature of the substitution.

obligatory replacement

Highlights the compulsory aspect of the replacement.

essential substitution

Stresses the importance of the substitution for a specific purpose.

needed replacement

Simple and direct, indicating a requirement for replacement.

compulsory change

Focuses on the mandatory aspect of altering something.

unavoidable alteration

Indicates that the change cannot be prevented.

imperative replacement

Highlights the critical nature of the replacement.

vital change

Emphasizes that the alteration is crucial.

critical replacement

Indicates the substitution is of utmost importance and urgency.

FAQs

How can I use "required substitution" in a sentence?

The phrase "required substitution" is used to indicate that a replacement or change is necessary. For example: "Due to the component failure, a "required substitution" was necessary to continue the experiment."

What's a simpler way to say "required substitution"?

You can use phrases like "necessary replacement", "needed change", or even just "had to replace" depending on the context.

Is it better to say "required substitution" or "necessary substitution"?

Both "required substitution" and "necessary substitution" are grammatically correct, but "necessary substitution" might sound more natural in some contexts. The best choice depends on the specific nuance you want to convey.

When is it appropriate to use the term "required substitution"?

The term "required substitution" is suitable in technical, academic, or formal writing where precision is important. In less formal settings, simpler alternatives may be preferred.