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Unfortunately, the serious environmental and health concerns related to hexavalent chromium mean there is an urgent need to find an alternative solution to achieve the required selectivity.
Following this, another procedure was developed for the quantitative evaluation of diosmetin glucuronide metabolites in human plasma; a micro-LC-MS/MS system was found suitable for obtaining the required selectivity and sensitivity.
The results cited herein can be useful to understand the nature of the inhibitor-target interactions, and furnish an insight on the structural/molecular requirements necessary to achieve the required selectivity against cyclin dependent kinases over other types of kinases.
When the recycle ratio approaches infinity, the required selectivity and pressure ratio reach their absolute minimum values, which have a simple relationship with that of a single-stage membrane process, as follows: Sn= S1, γn="γ1, where n is the number of stages.
As mentioned in the introduction, thorough optimisation of several key aspects of an analytical method is critical to achieve the required selectivity and sensitivity.
Intensive sample cleanup and enrichment by off line solid-phase extraction using cyclohexane followed by methanol and then distilled water was necessary to achieve the required selectivity and sensitivity in the reported method [21].
Similar(52)
Like the jazz masters he profiles, Mr. Burns knows how to tell a great story, and great storytelling requires selectivity, emphasis and omission.
It would require selectivity on the part of Pietersen though, and with the second new ball still hard and Johnson fresh, some application and fortitude from the others.
The application of anatomical research to clinical problems requires selectivity in choosing from numerous publications.
The energy envelope curve can provide a guideline from an energy perspective to determine the minimum required membrane selectivity in membrane process designs to compete with conventional separation processes, such as distillation.
Here, we have characterized piperazine and piperidine triazole ureas that combine the high potency attributable to the triazole leaving group together with the bulky aromatic benzodioxolyl moiety required for selectivity, culminating in compound JJKK-048 that potently (IC50 < 0.4 nM) inhibited human and rodent MAGL.
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