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News organisations and media companies have little choice not just to follow this path but to actually merge with it, if they wish to gain the required scale in this market.
GMG, whose purpose is to support the Guardian financially, decided to sell its regional media business to Trinity Mirror during the year, on the basis that GMG did not have the required scale in regional press to return the business to significant levels of profitability.
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The two images were scaled to have isotropic voxels; because the low-resolution images were obtained with an air objective, they were optically flattened compared to the high-resolution images and, thus, required scaling in the z-axis.
The technology part of the digital story, however, requires scale in order to be cost-effective.
The methodology establishes the required scale bridging in multiscale modeling for dispersion and transmission analyses, enabling rapid design and prototyping of local resonance metamaterials.
The variability of wind necessitates augmentation by other sources, primarily fossil fuels, because storage at the required scale is in most regions too expensive.
However, monetizing social networking isn't quite so simple, with many sites relying largely on a mixture advertising and affiliate e-commerce, which in return requires scale.
Improving access to methadone will require scale-up treatment slots in settings where methadone is currently available and removal of legal impediments to this evidence-based opioid treatment modality [ 20].
For on-demand services, profitability requires significant scale in areas with high population densities.
This suggests additional efforts are required in scaling up skilled birth attendants in Nepal.
For the heterochroneous analyses, estimates of Ne and generation times are required to scale times in units of 2Ne generations.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com