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The required remodelling of plasma membrane, resulting in phosphatidylserine translocation to the outer leaflet of the plasma membrane, occurs in platelets, endothelial cells and monocytes at sites of vascular damage or injury.
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Upon inspection, several regions required remodeling due to considerable deviations from the difference density maps.
In tissue engineering the effective repair requires remodelling of the extracellular matrix, particularly in the form of new matrix deposition.
Normal development of the facial primordia requires remodelling of the extracellular matrix, which is mediated in part by the matrix metalloproteinases (MMPs).
For DGN, binding to GALC requires remodelling of the active site pocket via movement of W524.
While medial SMCs can reduce wall stress temporarily through active constriction, long-term exposure requires remodelling of the vessel wall, typically resulting in an increase in SMC mass.
There is a close relationship between inflammation and the extracellular matrix (ECM), which requires remodelling to accommodate adipocyte growth during adipose tissue expansion.
This leads to several challenges: The use of modelbased tools in each stage often requires remodeling due to incompatibilities of the employed model formalisms.
As a result of these limitations, each iteration between design and analysis and vice versa requires remodeling of the object and conversion of its mathematical representation.
The repair of DNA double-strand breaks (DSBs) requires remodeling of the local chromatin architecture to allow the repair machinery to access sites of damage.
In our opinion, however, this observation does not exclude primarily DNA-influenced nucleosome positioning because positioning to the maxima of histone-DNA affinity may require remodeling enzymes.
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CEO of Professional Science Editing for Scientists @ prosciediting.com