Sentence examples for required refinement of from inspiring English sources

The final decision then depends on the degree of the required refinement of the educts, which in turn is a question of the effectiveness of substrate conversion and the price of the final product [67].

Application of this therapeutic modality to neurodegenerative lysosomal diseases requires refinement of neural cell targeting and CNS delivery methodologies.

Clarification of this issue may require refinement of methods to assess autophagic flux in the brain.

Surprisingly, with the exception of one research group, this feature has not been described in the literature and requires refinement of existing models of ion transfer across SLMs.

The complexity of molecular interactions within and among cancer cells, and between cancer cells and normal cells, which will require refinement of multi-agent treatment approaches against cancer.

The cloning of genes involved in such phenotypes requires refinement of the suspected genomic interval to as short a region as possible by linkage analysis.

This will require refinement of existing predictive and prognostic tools that are commonly employed by physicians to manage prostate cancer patients among different disease states.

To determine stresses and strains within microscopic structures, such as individual trabeculae, Haversian systems, cement lines or osteonal reversal lines, the lamina dura, or the tissue formed within several mm of the implant surface, would require refinement of the model to include such microscopic structural details and is beyond the scope of the current study.

The primers that we used for trnL will require refinement for application in metabarcoding of vascular plants from soil.

In the case of V. fischeri ES114, identifying interrupted essential genes was a significant clue that the sequence model required refinement, and those genes represent 12 of the 74 (16%) loci corrected (Table 1).

Those points required refinement and even re-formulation.