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The presence of metastatic tumor in bone was verified histopathologically at necropsy (Fig. 5d), but the decalcification required precluded tumor IHC assays for p27 and Ki67.
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Microfluidic systems have been developed to make and sort droplets, but the operator skill required precludes their ready implementation in nonspecialist settings.
TreeMap was not used in these experiments because the exponential time and space that it requires precluded its use for most of the problem instances.
Encasement or occlusion of the main portal vein or the left hepatic artery, if right lobectomy is required, precludes resection.
The occupants of residential care homes are, therefore, generally less dependent than those in nursing care homes, but the level of aid they require precludes them from living completely independently.
Notice is not required if precluded by military necessity.
Lactobacillus iners isolates were discarded since these bacteria require special growth requirements, precluding future large scale production and commercial application.
Because exposure to beryllium particles can cause adverse health effects, special care is required to preclude their contamination of personnel or atmosphere.
By accident, it immediately became critical to a mission rescue, as the craft?s solar shields failed on launch, and the new gyroscopic controls were crucial in the continuous spacecraft repositioning required to preclude fatal overheating.
The evaluation of FDRs in plant metabolome data indicated that, although accurate mass data obtained by TOF-MS have been widely used in assigning elemental compositions, a careful treatment of search results is required to preclude incorrect interpretations of metabolome data because of the relatively high FDRs for these results [9].
While mutation of both miR-125 target sites was required to preclude downregulation of the Cbx7-3′UTR reporter by miR-125, only the second miR-181 target site was important for downregulating Cbx7.
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