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He required patients to express clearly a wish to die.
The F.D.A. said that there was no public health emergency that required patients to immediately switch to other drugs.
But because researchers intended to assess the checklist's success, their work met the strict definition of "research," and thus required patients' informed consent.
Biovest might have succeeded because it required patients to first be in remission for six months or longer, so there was less tumor for the immune system to battle.
The insurer has not required patients to try an alternate cholesterol-lowering drug before Vytorin in the past and has no plans to do so at this time, Mr. Solow said.
In the same year, a smaller ECMO apparatus that could get patients up and walking — older versions required patients to remain supine and sedated — won approval from the Food and Drug Administration.
The program offered commercial insurance at a heavily discounted rate -- about $100 a month per person -- but required patients to use certain public hospitals and their doctors, an idea that many business owners found unattractive.
The study required patients to start chemotherapy within six weeks of their operation for the best chance of catching any remaining cancer cells.
The researchers also obtained some of their data from food questionnaires that required patients to recall details about their diets, a method that can be unreliable.
If required, patients were sedated with propofol and/or midazolam and analgesia provided with sufentanil.
Prien (Prien et al. [1973]) required patients to have had a manic episode.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com