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In two dimensions, the required neuron number will be no more than 5% of the minimum if the scale factor is within the range (1.43, 1.96) for the winner-take-all model and the range (1.28, 1.66) for the probabilistic model.
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The approach introduced in adaptive connecting-and-pruning algorithm (ACP) is a type of mixed mode operation, which is equivalent to pruning or adding the connecting of the neurons, as well as inserting some required neurons directly.
If required, neurons were transfected with synaptopHluorin under control of a synapsin promoter [32] on DIV3 with a modified calcium phosphate method as described [33].
In our final two predictions, we sought to move neurons in the opposite direction across their tipping point, which required neurons rendered hyperexcitable by nerve injury ('Materials and methods').
We then fix this resolution as being behaviorally determined and minimize the number of required neurons while allowing the periods of the modules, and, crucially, the number of modules, to vary to achieve the minimum.
Large-scale simulations of cortical activity and theoretical investigations of neuronal dynamics require neuron models that are mathematically tractable, biologically relevant and computationally fast.
The code requires NEURON and Python and has been tested on Linux machines (Red Hat and Ubuntu).
The neuronal implementation of EC1 and EC2 require neurons with the following properties.
Yet there are ways to store information biologically that don't require neurons.
The findings, described in the Proceedings of the Royal Society B, contradict the idea that learning always requires neurons, and may shed light on the early evolution of learning in living things.
Repair of the CNS will require neurons or oligodendroglial cells produced, preferably, from autologous sources.
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