Sentence examples for required marker from inspiring English sources

Because the required marker density is low, the W-FAM strategy can also be useful for species for which no dense SNP-chips are available.

Interest toward LD recently has been fueled by its fundamental role in determining the required marker density and feasibility of gene mapping approaches (Jorde 2000; Zondervan and Cardon 2004).

Similar results on the required marker density for prediction purposes in elite germplasm of maize were reported by Riedelsheimer et al. (2012), who found that the prediction accuracy did not increase markedly when increasing the number of markers beyond 2500.

Thus, the required marker density in real data might be higher than indicated by the simulations, because the selection of SNPs on minor allele frequency performed in the simulations causes higher linkage disequilibrium between the SNPs than expected from the SNP density.

Today, the availability of high-density SNP platforms that can assay more than 0.5 million loci offers the required marker density.

Alternatively, producing different sLL prelabeled for all required markers is another approach, but one that would greatly increase costs.

Importantly, the genotyping cost is reduced because the number of required markers in an AIM panel is significantly diminished after inclusion of ancestry informative GE markers.

Here, we conclude that the CD3, CD4, CD25, CD127, and FoxP3 markers are the minimally required markers to define human Treg cells.

This large disparity in the number of required markers is caused by the different length in the marker interval with a significant LD intensity in an unrelated mapping population and full-sib families.

GE supplies ethnic information supplemental to SNPs; this motivated us to integrate SNP and GE markers to construct AIM panels with a reduced number of required markers and provide high accuracy in ancestry inference.

Based on the data presented here and taking into account the above-mentioned considerations, we consider the use of the CD3, CD4, CD25, CD127, and Foxp3 markers as the minimally required markers to define human Tregs.