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It is shown that the proposed method can lead to significant improvements in the definition of an optimal progress variable over conventional formulations, essentially eliminating the expert knowledge previously required in identifying such quantities.
However, greater understanding is also required in identifying the upstream elements capable of disrupting the expression profile of miRNAs, including environmental factors, ultimately resulting in disease.
Only a minority of our RR sera reacted with IMPDH2 and none reacted with CSP1, suggesting more effort is required in identifying the related target autoantigens.
A high index of suspicion is required in identifying DCIS and the MRI screening studies will produce valuable information giving a much more accurate estimate of the ability of MRI to detect in situ disease.
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This requires skill in identifying creditworthy customers, which fintech outfits reckon they can do better than banks.
This will require innovation in identifying, characterizing, and recapitulating key aspects of three-dimensional (3D) tissue architectures to study dynamic cell-microenvironment relationships.
It has been pointed out, however, that students are not always capable of recognising areas where further practising is needed [ 21, 22], and may require guidance in identifying the next steps to be mastered.
Notice that for the target receptor, a bound ligand or a user defined ligand is required to aid in identifying the binding pocket.
Targeting the PI3K pathway appears very promising, although more extensive study is required - particularly in identifying patients who will benefit.
Large numbers of markers, such as Simple Sequence Repeats (SSRs) and Single Nucleotide Polymorphisms (SNPs), are required to assist in identifying genes that underlie genetic variation.
Validation data is required in order to identify and estimate all parameters.
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