Sentence examples for required for this checkpoint from inspiring English sources

The exosome subunit Rrp6 is required for this checkpoint in Saccharomyces cerevisiae, but it is not known whether Rrp6 also plays a role in mRNA surveillance in higher eukaryotes.

We conclude that Mrc1 is not required for the checkpoint response to cdc13-1 dependentelomerere uncapping.

Furthermore, the results provide an initial indication that Aurora B activity is required for the checkpoint response in the absence of microtubules.

The function of the FHA domain is largely unknown but is required for the checkpoint function and might be involved in the binding to phosphorylated proteins [ 19].

We also examined if the different mec1 alleles interacted with Lcd1/ Ddc2 (ATRIP in mammalian cells), an association required for the checkpoint functions of Mec1 (Rouse and Jackson 2000; Paciotti et al. 2000; Wakayama et al. 2001).

In addition, we have previously shown that Aurora-dependent phosphorylation of budding yeast Mad3p is required for the checkpoint response to lack of tension at microtubule-bound kinetochores [6].

Inactivation of rna14 leads to accumulation of Bub1-GFP foci, a protein required for spindle checkpoint activation that could be due to the defects in the attachment of mitotic spindle to the chromosome.

Chk1 is required for spindle checkpoint function, both in normal and in taxol-treated cells [45].

These results indicate that Ybp2 is not required for spindle checkpoint function.

Furthermore, IR-induced ERK1/2 signaling is required for G2/M checkpoint activation after IR [ 16].

Based on functional analysis of Chfr deletion mutants, both the FHA and CR regions are required for its checkpoint function.