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The dichotomy of the ΔDAS28 (on average comparable with a 20% improvement in DAS28) was chosen because it is applied in daily clinical practice and required for prolongation of reimbursement for TNFα blocking therapy by insurance companies in The Netherlands.
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In the nematode Caenorhabditis elegans, autophagy is required for lifespan prolongation mediated by caloric restriction [ 72- 74] or p53 depletion [ 22, 49, 75- 77].
Only when using Ringer's lactate for both the first and second fluid infusion was there a significant prolongation of the time required for overcoming the surgery-induced paralytic ileus and food intolerance.
Registration required for both.
required for the job.
"What interest can the state possibly have in requiring the prolongation of a life that is all but ended?" he wrote.
This definition does not necessarily require a prolongation of hospitalization or patient disability nor implies any assumption about the severity of the AE.
- requires hospitalisation or prolongation of existing hospitalisation, excluding those planned for cancer treatment, disease related procedures, or placement of an indwelling catheter, unless associated with other serious events.
4, 73, 74 Severe acute OXLIPN (oxaliplatin-induced peripheral neuropathy) that requires prolongation of oxaliplatin infusion or treatment discontinuation may occur in up to 22% of treated patients.
These include death, life-threatening events, events that require hospitalisation or prolongation of existing hospitalisation, and persistent or significant disability/incapacity.
It is clear that other unknown factors within FCM are also required to achieve efficient prolongation of neutrophil survival.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com