Sentence examples for required for nephron from inspiring English sources
Ureteric branching is required for nephron formation.
Redundancy between these FGFs has also been demonstrated in kidney development, where both ligands are required for nephron progenitor maintenance (Barak et al., 2012).
Several Wnts are expressed during kidney development, and activation of the Wnt pathway can result in localization of β-catenin to the nucleus where it activates a pattern of gene expression that is required for normal nephron development [Karihaloo et al., 2005].
While SHH signaling is not required in the medullary collecting ducts themselves, the absence of signal in cortical ureteric cells, contributed to by diminishing SHH concentration and/or pathway inhibitors, is critical for ureteric tip cell gene expression required for ureteric branching and nephron induction.
40 As cilia are required for the proper development and maintenance of nephrons in kidney, the absence of cilia due to the loss of VHL apparently results in the formation of lesions in kidney tissue, leading to tumorigenesis.
In the proximal tubule, the sodium-bicarbonate (Na+-HCO3−) cotransporter NBCe1 mediates basolateral electrogenic sodium-coupled bicarbonate transport and is required for bicarbonate (and sodium) recovery on this segment of the nephron [ 25].
Registration required for both.
Urinary cathepsin B activity, a lysosomal tubular proteinase, was proposed as a marker for nephron numbers as it had the strongest inverse correlation with other markers of nephron endowment [39].
Our data therefore identifies a molecular network for nephron patterning.
Thus, we used 24-h CCr as a marker for nephron number.
