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Caf1 and Ccr4 are required for integrity of heterochromatin islands and subtelomeric regions.
SIRT3 serves as a mitochondria-localized tumor suppressor and is required for integrity and metabolism of mitochondria during stress [ 17].
Deplus et al. (2013), in contrast, proposed that Tet-tethered Ogt O-GlcNAcylates Hcf1, a process that the authors surprisingly claimed to be required for integrity of the H3-K4 methyltransferase complex Set1/COMPASS.
For example, gliotoxin produced by the filamentous fungus Aspergillus fumigatus is required for virulence of this pathogen in both flies and mice (Spikes et al., 2008), and Cas5 has been shown to be a transcription factor regulating a set of genes required for integrity of the cell wall of C. albicans (Chamilos et al., 2009).
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Microtubules were proposed to be responsible for T-DNA trafficking; however, our study found that the integrity of microtubule structure was a restricted factor for the AMT process and that ARP6 was required for the integrity.
Likewise, the actin cytoskeleton is required for cadherin integrity at cell cell contacts.
Bratic, A. et al. Mitochondrial polyadenylation is a one-step process required for mRNA integrity and tRNA maturation.
Myosin VI is required for structural integrity of the apical surface of sensory hair cells in zebrafish.
In neurons, the tetramerization is required for structural integrity of the dendritic spines and recruitment of proteins to synapses.
Mutant analyses indicate that the cardia bifida locus natter (nat) is required for the integrity of the myocardial epithelia.
Nakayama, J. et al. Alp13, an MRG family protein, is a component of fission yeast Clr6 histone deacetylase required for genomic integrity.
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CEO of Professional Science Editing for Scientists @ prosciediting.com