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In contrast, the CDC27 ubiquitin ligase is required for evading lysosomal fusion and for phagosomal escape into the cytosol.
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Understanding mechanisms by which apicomplexan parasites evade immune or chemotherapeutic elimination is required for development of effective vaccines or chemotherapeutics.
In comparison to their small molecule counterparts, proteins can adopt large and precisely defined three-dimensional surfaces required for binding and controlling complex biological targets that have evaded small-molecule regulation.
BAX expression is downregulated in hypoxia (Erler et al, 2004) and suppression of the pro-apoptotic BAX/BAK pathways is required for tumour cells to survive in hypoxic conditions and evade treatment-induced apoptosis (Nelson et al, 2004).
The Court of Appeal said it was sympathetic to the argument that the issues raised were likely to evade judicial review, due to the required revision of the plan every four years and the time required for review.
Further investigations are required for the cell-mediated immunity in the light of Ad-loaded MSCs and for the strategy to evade host immunity such as use of immunosuppressive agents.
VP35 is a cofactor in the RNA polymerase transcription complex, and helps the virus evade the immune response by blocking activation of the interferon regulatory factor 3, which is required for the induction of interferons alpha and beta.
Genes required to evade the host innate immune response are common.
When and why do transforming or transformed cells require mechanisms to evade apoptosis?
Successful infections require viruses to evade host defenses and use cellular resources and machinery to produce new virions.
As time went by, techniques for evading the ban developed.
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CEO of Professional Science Editing for Scientists @ prosciediting.com