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Power plants are key elements of national infrastructure and eco-friendly solutions are required for commitment to the society.
Huang, H. et al. BMP signaling pathway is required for commitment of C3H10T1/2 pluripotent stem cells to the adipocyte lineage.
SIRT1 was required for commitment to the MK lineage and subsequent maturation, but was not directly involved in polyploidization of either K562 cells or an already-MK-committed cell line, CHRF-288 11. CHRF-288 11
During T cell development, Notch signalling is required for commitment of the earliest progenitor, and may also function during other developmental stages.
These data imply that such polycomb proteins could be responsible for maintaining progenitor cells by repression of genes required for commitment to differentiation.
Therefore, these data strongly suggested that C/EBPβ and C/EBPε are required for commitment of hematopoietic progenitor cells under cytokine stimulation to myeloid cells.
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By conditionally deleting Zfpm1 and Gata1, we observed that loss of the former prevented specification of all Mk/E-committed progenitors, whereas Gata1 was required for the commitment of bipotent preMegEs towards an erythroid fate.
But the examples of implicit commitment considered in §1.7.4 and §1.7.5 suggest that sufficiency is not required for ontological commitment.
Although the molecular basis for floral commitment remains unclear, recent studies suggest that the persistent activity of FLOWERING LOCUS T (FT) at inflorescences is required for floral commitment in Arabidopsis thaliana.
This complex is therefore different from the "stable complex" minimally required for template commitment.
Although Hedgehog signaling is required for endodermal commitment and hepatogenesis, the possibility that it regulates liver turnover in adults had not been considered because mature liver epithelial cells lack Hedgehog signaling.
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