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Our data suggest that TLR(s) play a role in the recognition of E. muris since MyD88, but not caspase-1, is required for a response against E. muris infection in DCs (Figure 4 and 5).
Note that some factors may increase the likelihood of a response (i.e., decrease the minimum dose required for a response), while others may decrease the likelihood of response (i.e., increase the threshold dose).
The sub-randomisation between 5-day and 21-day schedules in this trial also provided a framework for the investigation of the hypothesis that higher intensity of temozolomide treatment might be required for a response, if one or two unmethylated copies of the MGMT gene are present.
Be careful to include all the elements that are required for a response.
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A basic precept is that the TCR reads different potencies of activation to initiate different effector outcomes with the 'strength of stimulation' required for a Th1 response greater than for a Th2 response [ 9].
Systems running this kind of algorithms usually are required for a rapid response, something that a PC hardly can provide.
The low absorbed doses required for a haematological response in patients undergoing external radiotherapy may reflect the fact that patients with haematological disorders have other predisposing factors.
Meropenem exposures from 15 children (8 17 years old) with cystic fibrosis (CF) acute pulmonary exacerbation were analyzed to define the pharmacodynamic threshold required for a positive response.
The petitions aren't likely to be taken seriously -- neither has more than a few hundred signatures out of 100,000 required for a White House response -- but they do reflect a tone that has been used to criticize the hardline Republican approach to the ongoing debate over funding the government and avoiding a looming shutdown.
This indicated that the CtrA and FlaA proteins were not required for a directional response to broad spectrum white light.
Therefore DR is not independent of either SIR2 or FOXO, despite neither being required for a DR response.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com