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We postulate that the spleen provides either a required niche or a required factor(s) for JAK2V617F-expressing hematopoieticellsls to maintain the high hematocrit that characterizes PV.
In contrast, ATP is a maintained and required factor for apoptosis.
Considering this, it was surprising that the knock-down of a gene which encodes such a widely required factor would lead to such a specific cuticle phenotype in Tribolium.
The regulation of genes in the flavonoid/anthocyanin biosynthetic pathway requires multiple transcription factors, and it is also possible that another required factor for fht1 upregulation is not present in the ear shoots.
Inositol has not been established as an essential nutrient for humans; however, it is a required factor for the growth of some yeasts and fungi.
Recently, the p38 MAPK was identified as a required factor optimizing CAR activation and CYP2B6 induction in liver cells (Saito et al., 2013).
Similar(44)
Values allotted to each "prioritization required factors" were divided by those allotted to each "reducing factors".
The proposed prioritization technique is based on the idea of identification of "prioritization required factors" and "reducing factors".
Cost and penalty were identified as reducing factors while Benefits, value, Risk, Time to Market and dependencies are categorized as prioritization required factors.
Abuse can occur alongside the required factors but on its own does not explain attachment disorder.
Expression, replication, and maintenance of mtDNA require factors encoded by nuclear genes.
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