Sentence examples for required disruption of from inspiring English sources
This observation further supported our above hypothesis that the G protein-mediated inhibition of NMDA channels by DHPG required disruption of the mGluR1a/Homer c-c/Shank3, but not NMDA-R/PSD-95/GKAP complex.
In a fracture repair setting, this required disruption of the periosteum and trauma to the local tissues.
More recently, a synergistic action of both mammalian chitinases in antifungal immunity has been demonstrated in a rat model of aspergillosis (although this required disruption of the cell wall with caspofungin) (Verwer et al., 2013), a situation reminiscent of the concerted action of chitinases and β-1,3-glucanases in antifungal plant immunity (Jongedijk et al., 1995).
Current spine arthroplasty devices require disruption of the annulus fibrosus for implantation.
The ability of HGF to induce epithelial cell morphological changes and motility requires disruption of cell-to-cell adhesion and dissociation of the basal lamina from the extracellular matrix [13],[13].
This unstable injury requires disruption of the ligaments between the occiput and C1, and commonly results in severe stretch or laceration injury to the upper spinal cord and brainstem [8].
Entry of EEV requires disruption of the outer viral membrane either at the plasma membrane or in endosomes [14], [15], [16].
At present, it is unclear how cycling of NOXO1 between these two states is regulated and what the molecular details of this active state are, but our data suggest that full activation will require disruption of the intramolecular interaction between the tandem SH3 domains and the proline-rich region.
The intrinsic pathway requires disruption of mitochondrial membranes and release of cytochrome C [ 2].
ErbB2/HER2-induced transformation of 3D structures, but not cell proliferation, requires disruption of the Par6 cell polarity pathway [ 4].
Ingression of cells during gastrulation requires disruption of a RhoA-dependent mechanism required for stabilization of basal microtubules in epiblast cells (Nakaya Y et al, NCB, 2008).
