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BAP/BAP mice display strongly regionalised segmental phenotypes, indicating that Hes7 activity, like that of Lfng, is required differentially during the course of somitogenesis.
Our finding that β-catenin is required differentially in mouse acini and islets emphasizes its cell-type-dependent role in proliferation.
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Collectively, these results suggest that the Notch signaling pathway TF Su H) is required for differentially regulating appropriate enhancer activities in PCs, and is crucial for mediating the lineage decision between PCs and CCs.
The genomes of numerous Wolbachia strains are known to encode two phage-derived adenine methylases (Saridaki et al. 2011), and homologs of these genes are present in wMel, wMelCS, and wMelPop, suggesting that these strains have the genetic machinery required to differentially methylate their genomes.
In summary, our results show essential genes are differentially required and their requirement level appears to reflect the extent of predicted protein-protein interactions.
Hence, it has become increasingly common to require that differentially expressed genes satisfy both p-value and fold-change criteria simultaneously.
This fact rules out age effects as a confounding factor because our feature selection algorithm requires selected differentially methylated probe sites to remain consistently low across controls, leading to large overlaps in the ages associated with the three CIMP categories.
This is evidenced by the fact that Adr1 and Cat8 are differentially required for nucleosome remodeling at ADH2 and FBP1 (Fig. 3).
The genes in the subnetwork are further required to be differentially expressed before and after the invasion of the pathogenic fungus.
Given the enhanced pathological angiogenic responses in β3-null mice [12] we asked whether endothelial Rac1 was differentially required in tumor angiogenesis in adult wild-type or β3-null mice.
Subsequently, a network was extracted from PPIN that consists of genes that interact with seed genes, where the genes were further required to be differentially expressed before and after the invasion of the pathogenic fungus.
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CEO of Professional Science Editing for Scientists @ prosciediting.com