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The minimum required allele frequency can be set when the workflow is run.
In order to increase the reliability of SNP-MaP allele frequency estimates, we required allele frequency estimates from a minimum of 6 (out of 10) replicates for both high and low groups.
In order to increase the reliability of SNP-MaP allele frequency estimates, we required allele frequency estimates from a minimum of six (out of 10) replicates for both high and low groups.
In order to increase the reliability of SNP-MaP allele frequency estimates, we required allele frequency estimates from a minimum of 3 (out of 5) pools for both high and low groups.
Similar(56)
In contrast, IBS can be calculated without knowledge of pedigree structure and does not require allele frequency information.
AWclust does not assume Hardy-Weinberg equilibrium or linkage equilibrium and does not require allele frequency estimates.
A similar approach with additional conditioning on parental candidate marker genotypes, which does not require allele frequency specification, led to some power loss.
The regression method does not require allele frequencies to obtain G, the realized genomic relationship matrix.
This SNP set required an allele frequency difference of ≥2% between the study population and a group of 301 Holstein cattle that have remained unselected since 1964 to allow identification of near-fixed alleles in the contemporary population due to selection.
However, DHW calculations require allele and genotype frequencies to be from the same time point (i.e. post-selection).
Genotypic data were accepted after quality control as described elsewhere [ 20], requiring minor allele frequency (MAF) >0.0001, Hardy-Weinberg equilibrium (HWE) P >0.001 and genotyping success rate >0.99.
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