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Taking these assumptions into account, the required accumulation time for the S-WPIA is estimated to be at least 18 spin periods, corresponding to 144 s.
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Changes in codon bias would not become apparent for some time, given that this requires accumulation of synonymous substitutions.
However the relatively small number of human cases of MVEV disease and their irregular occurrence is a challenge and requires accumulation of data over a long period of time.
The level of offspring care may not easily be assessed by breeders, as it requires accumulation of information of an individual's work rates over a prolonged period of time.
Using state-of-the-art low-noise pre-amplifiers and low-noise electronics, it should be possible to significantly reduce the accumulation times required to observe spin noise in the future.
We also estimate the number of particles required to obtain statistically significant results with the S-WPIA and the expected accumulation time by referring to the specifications of the MEP-e and assuming a count rate for each detector.
If the number of particles required in order to increase the statistical significance of the obtained results is set at 12,000, the accumulation time should be greater than six spin periods in the pitch angle range from 60° to 120°.
This improvement was most pronounced at lower sample concentrations, where extended ion accumulation times are required, resulting in an ∼2-fold increase in the number of protein identifications.
Accumulation time: 30 s.
Accumulation time: 30 s and accumulation potential: -0.8 V.
The spectrum accumulation time was 120 s.
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