Sentence examples for required a significant effort from inspiring English sources

This required a significant effort in manual inspection to discard those models containing knots (Rohl et al., 2004a), but this step was necessary as the assessors in CASP4 had deemed knotted models 'impossible structures' (Tramontano et al., 2001).

Several securities regulators involved in the investigation said that bringing a case against a firm that did not retain all its e-mail messages would require a significant effort.

It requires a significant effort to measure it experimentally.

Furthermore a diverse range of tools requires a significant effort to orchestrate the communication between these tools.

The implementation of the Newborn Individualized Developmental Care and Assessment Program (NIDCAP) requires a significant effort from all professionals involved.

Maximizing the benefits from existing observational schemes "will require a significant effort in capacity building for developing countries," says Patricio Bernal, executive secretary of the International Oceanographic Commission.

As a result certain choices in software design are taken implicitly, resulting in dedicated functions for which comparing and adapting the algorithm requires a significant effort.

SIP License Agreements may require a significant effort depending upon the business objectives of the parties, the intended use of the SIP Product, the nature of the SIP product, and the risks associated with using the SIP product in the end application.

Even the first step, identifying the species and genes studied, may require a significant effort (5, 6).

(Perhaps these data are already available?) Although our results do predict this result, testing it would require a significant effort.

However, the development of this information would require a significant effort since each subject (case and control) would require its own history based on the event date.