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Molecular biomarkers for ionizing radiation exposure (gene expression changes, blood proteins) can be measured in real time using such diagnostic detection technologies as miniaturized nucleic acid sequences and antigen-based biosensors, but they require validation of dose-dependent targets and development of optimized protocols and analysis systems.
A basic level asks for user ID and password; that can require validation of e-mail address.
Most online learning systems require validation of IDs to ensure that the individual enrolled in the course, completing the assignments and taking the tests is in fact who they say they are.
The new rules will require companies drilling on public lands to disclose the chemicals they are using to the Bureau of Land Management, will set higher standards for the storage of wastewater from the fracking process, and will require validation of well integrity.
Lastly, the ideal curriculum would require validation of its objective and content [ 31].
To consider the reported concentrations as accurate would require validation of the developed procedure using a certified reference material.
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Many of the text mining systems required validation of the results at the sentence level (in many cases validating redundant information), whereas the biocurator decides at the abstract/document level.
External corroboration of microarray results using PCR-based methodology also requires validation of appropriate internal reference genes for normalization of expression values.
The proposed development of a High Speed Civil Transport (HSCT) required validation of the role of high-energy neutrons, and this resulted in ER-2 flights at solar minimum June 1997 and studies on effects of aircraft materials on interior exposures.
Traditional drug development requires validation of the efficacy in animal models of same disease entity.
Our two-stage analysis allowed us to control Type I error by requiring validation of our results in a second sample.
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