Reliable and established newspaper and magazine editors require substantiation for stories before they go to print.
CAD assesses and requires substantiation for claims in ads, like "25% more power", "environmentally friendly", "the world's biggest/smallest/ fastest".
These hypotheses do however require substantiation in future studies.
Specifically, conclusions regarding dynamic instability and organization of filaments in spindle-like structures of infected cells made on the basis filament tracking data require substantiation.
2. The paper makes some claims, which require substantiation, or should be reconciled with literature, or should be altogether eliminated.
Nevertheless, such claims require substantiation and it has been shown that TKA at best, only modestly improves physical activity levels [ 2].
Cerebellar atrophy was a relatively consistent feature in individual cases here, although whether this is truly a signature of C9ORF72-associated FTD requires substantiation in larger patient cohorts from different centres.
As a consequence, an indirect comparison of practice-related changes in motor performance with muscle activity was performed that requires substantiation by further studies that directly compare practice-related alterations in motor performance associated with changes in muscle activity via correlational analysis.
While the evidence of their benefit for prevention of malignancies requires substantiation, the observations that vaccinations with BCG and/or vaccinia early in life improved the outcome of patients after surgical therapy of melanoma are of practical relevance as the survival advantage conferred by prior vaccination is greater than any contemporary adjuvant therapy.
For example, the hypothesis that changes in inspection time for a previously encountered place or object are based on the recall of declarative/episodic information requires substantiation.
The suppression of hyperammonia development with norvaline or agmatine probably reflects an inhibition of arginine deiminase, but this requires substantiation.
