Sentence examples for require phosphorylation for from inspiring English sources

Expression of IRF9, the DNA-binding component of ISGF3 that does not require phosphorylation for activity, was equivalent in both cell lines prior to addition of IFN-α.

Both of these sites require phosphorylation for full catalytic activity.

In the nucleus, phosphorylation is equally important as TFs required for immunity (e.g. WRKY and ethylene-responsive type TFs) often require phosphorylation for their activation [ 25].

For kinases that require phosphorylation for activity, the phosphate moiety at the primary phosphorylation site stabilizes the activation segment in a conformation suitable for substrate binding, whereas in the inactive unphosphorylated state, the activation segment is usually largely unstructured (Goldberg et al, 1996; Sicheri et al, 1997; Meng et al, 2002).

Perhaps only one of these sites in the OX2 receptor requires phosphorylation in order for the receptor to adopt a high-affinity state for arrestin binding.

Conversely, tau requires phosphorylation by GSK3β for efficient recognition and ubiquitylation by the CHIP/Hsp90 complex [ 61].

However, DAPK3 has been reported not to require activation segment phosphorylation for catalytic activity.

Non-fermentable carbon sources require mitochondrial oxidative phosphorylation for their utilization suggesting that deletion of VPS35 in yeast may impair mitochondrial respiration.

This data confirms that CK1α phosphorylates Ser45 while GSK3β is required for phosphorylation of Thr41, Ser37, Ser33.

Thr87 and Lys109, although not absolutely required for phosphorylation, have been implicated in contributing to the phosphorylation-induced conformational change [ 22- 24].

Strikingly, their studies show that RAD51C is required for phosphorylation of CHK2 by ATM, which is required for checkpoint activation.