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Re-computation of alignments for largely the same sets of sequences is wasteful and may occasionally introduce errors that require manual verification and corrections.
The quality of the sequences is very high and differences to genomic DNA minimal, confirming that the enzyme discovery method described in this study for high-throughput applications would not necessarily require manual verification of the sequencing by laborious Sanger sequencing of amplified genomic DNA.
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Currently, the process of fusing multiple image techniques in radiation oncology is labor-intensive and requires manual verification of the quality of the registration by qualified experts [ 35].
T K classification : The TK group is thought to have arisen on the branch that gave rise to metazoans after divergence from the fungal branch (Manning et al., 2008); classification of earlier-evolving TK group members thus requires manual verification.
Although such search strategies are difficult to threshold and require manual follow-up and verification, they represent examples of data mining efforts which are well within reach for experienced ToxoDB users.
While MATLAB and Simulink require manual formulation of equations and block diagrams characterizing the controlled system, DYNAST allows for the system simulation, thorough verification and diagnostics without any such time consuming and error prone drudgery.
Both require manual dexterity and practice.
But most require manual focusing on the G1.
Others require manual syncing.
Such signals require manual approach or approximations.
The Department of Agriculture USDAA), which oversees the scheme, requires manual, paper-based verification of applicants, based solely on the information they provide.
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