Mitochondrial transplantation provides an efficacious cardioprotective protocol that can be used either as an exclusive intervention to ameliorate myonecrosis and enhance myocardial function or could be used as a primary intervention prior to subsequent auto-, allor or xeno-geneic cellular regenerative interventions requiring extended times for cell isolation, purification and expansion.
Follow-up of a randomized trial is ideal for internal validity but requires extended time, may lack external validity, and is not useful for monitoring.
For my partner's mother's seventy-second birthday, an occasion about which she was feeling down, I made a roast lamb that required extended time and concentration, as any birthday meal should.
Furthermore, some QOL domain measures may require extended periods of time before significant changes are observed.
The reaction with 8 proceeded more slowly than other examples, requiring extended reaction times for good yield, presumably due to increased steric bulk.
However, cutaneous wound healing is a major interest for the public health sector because the skin wounds affect a large number of patients, seriously reducing their quality of life, requiring extended hospitalization time, and accounts for a significant amount of healthcare expenditures.
It requires extended periods of time without having a permanent home and limited, if any, time with loved ones.
Current procedures for efficient DNA precipitation are time consuming requiring extended incubation at cold temperature and/or extended centrifugation time at high speed.
The relatively low concentrations of compounds (in the ng to μg/g range) present in samples, however, may provide a plausible explanation for the extended time required for kidney failure and upper urinary tract cancer to develop in BEN patients.
