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However empirical tests of this framework are rare and require demonstration that historical associations among elements of deterministic network are not themselves modified by recent evolution.
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A more convincing test of this hypothesis requires demonstration that fertility within modern populations covaries with the magnitude of trade-off effects.
So, strictly, demonstration of full time compensation requires demonstration that deviation in orientation under clock shift is not dependent on the time of day at which the birds are trained and released.
The Common Rule states that institutional review board approval requires demonstration that "risks to subjects are reasonable in relation to anticipated benefits, if any, to subjects, and the importance of the knowledge that may reasonably be expected to result".
The permitting process for hydrogen fueling stations requires demonstration that the proposed facility meets certain safety requirements.
Development of new formulations after the original testing of any drug requires demonstration that the compounds are therapeutically equivalent and additional efficacy studies may not be required.
Implication of a microbe in a disease via Koch's postulate requires demonstration that an agent is specific for that disease, and that disease can be reproduced in a naïve host by inoculation with the agent propagated in culture following isolation from an affected host.
In the special case of frequency-dependent selection, it requires demonstration that the minor allele is always advantageous.
Despite the practical predictiveness of Years 1 and 2 relapses, validation as an outcome still requires demonstration that suppression of these relapses translates into suppression of long-term disability.
Convincing funders to support a trial required demonstration that such an intervention in a developing country setting could indeed influence blood pressure in the first place.
The guidance requires demonstration that a drug not be associated with the increases in CV risk outlined by Nissen, which indeed might require 4 6,000 treatment years of follow-up of high-CV risk patients.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com