Sentence examples for require a timeframe from inspiring English sources

However, whereas the initial activation of cellular signaling occurs within minutes to hours, the adaptation to a certain cellular behavior frequently involves profound structural changes within the cells that require a timeframe of hours to days.

Since phase III definitive efficacy trials with cancer endpoints require a lengthy timeframe and considerable resources for completion, it is critical to first optimize agent delivery and trial design and to determine preliminary efficacy via the conduct of phase II trials.

Therefore, it is likely that such an additional effect requires a longer timeframe in between assessments.

Policy evaluation requires a longer timeframe than political exigencies often allow.

Some of the discrepancies between our registry and physician claims algorithms for chronic dialysis likely relate to differences in the classification of patients who receive temporary dialysis or who die soon after initiating dialysis Traditionally, administrative algorithms and national registries, such as the USRDS, have required a 90-day timeframe to define chronic dialysis [ 19, 20].

Obtaining such data within a meaningful timeframe requires a fundamental change in the planning and setting up of research studies.

This requires a judgement of appropriateness in the context of benefits and burdens within the timeframe of estimated prognosis.

Producing evaluative evidence of this type requires a lengthy duration and it is widely recognised that programmes require feedback within shorter timeframes than is often possible through the 'typical' research cycle [ 41, 42].

In particular, direct optimization of simulation models, typically, requires a large number of model evaluations, which may be impractical or even infeasible in a reasonable timeframe.

The synthesis required a combination of secondary framework and thematic analysis approaches and was conducted within a health technology assessment timeframe.

Should the department fail to complete the repairs within a required timeframe the tenants can lodge claims with the NT Civil Administration Tribunal.