Sentence examples for require a profound change from inspiring English sources
To undo the damage will require a profound change of political direction.
This, the consultant's report stated, will require a profound change in the way Yale manages its nonacademic work force and the way the two unions represent their 3,900 members.
Turning an epithelial cell into a mesenchymal cell requires a profound change in genetic and epigenetic programs leading to alterations in morphology, cellular architecture, adhesion, and migration capacity [ 11].
This "left-shift" in the gestational age of the affected population, during which time critical events in lung development are occurring, has required a profound change in our investigation and understanding of both the histopathology and pathophysiology of BPD.
To achieve such a profound change would require a radical first step.
Disavowal of all violence on moral or religious grounds requires a more profound change (hence, evokes greater resistance) than personal disengagement from violence (e.g. on the grounds that one has done one's share) while condoning it for others (Kruglanski et al., 2013; Reinares, 2011).
Tuesday's results signaled a profound change.
He was undergoing a profound change.
The result was a profound change in policy.
For the tribe, this brought on a profound change".
