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For structural components under random loading, realistic fatigue life predictions require a damage accumulation law together with a cycle counting method.
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Similar results have been documented for the mTOR inhibitor, rapamycin [5], [6], and the eIF4A modulator, silvestrol [17], and suggests that the tumors derived from the Eμ-Myc model require a DNA damage trigger to undergo apoptosis when translation is inhibited.
Alternatively, the inability to detect this relationship at baseline may have reflected the short duration of disease in these patients, as an impact on physical function may require a threshold of accrued damage not yet achieved at baseline.
In-service damage, for example crash or battle damage, may require a customised repair procedure that must be supported by engineering analysis.
To undo the damage will require a profound change of political direction.
The site lets hosts require a rental deposit to cover damage or other problems.
As a result, Mir has lost half its electrical power.Repairing the damage will require a spacewalk, but that must await the arrival of another Progress carrying a suitable repair kit.
They are also the places where most forest is most directly threatened by an exploding human population.Limiting the damage will require a global rethink of land use, which capable countries must lead.
While workers were able to get the line running through the tunnel two months after the storm, it was clear that the damage would require a more extensive repair effort, according to the Metropolitan Transportation Authority.
Developing therapies for protecting healthy tissue from damage will require a better understanding of the biological pathways activated by radiation.
However, they do give less damage and require a 2-block deep hole to place them in.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com