Sentence examples for reprogramming with from inspiring English sources
The differences in methylation and demethylation activity during reprogramming with Yamanaka and Thomson reprogramming factors can provide a rationale for selecting reprogramming factors and reprogramming efficiency-enhancing epigenetic drugs.
Lineage-tracing experiments showed that the cardiac reprogramming with GMT was a direct conversion process.
Additionally, in vivo reprogramming with the polycistronic MGT vector produces greater functional improvement in fractional shortening and ejection fraction and reduces scar size following myocardial infarction than reprogramming with separate viruses (Ma et al., 2015).
In vivo reprogramming with polycistronic MGT following coronary artery ligation increases the number of α-Actinin/β-galactosidase double positive iCMs compared to reprogramming with separate Gata4, Mef2c, Tbx5 viruses (Ma et al., 2015).
These iCMs exhibit accelerated reprogramming with beating cells observed as early as one week after reprogramming (Mohamed et al., 2016).
The other four constructs decreased αMHC-GFP iCM reporter expression compared to reprogramming with separate viruses (Wang et al., 2015a).
Reprogramming with miR-133 also generates more iCMs exhibiting spontaneous calcium oscillations than transcription factor cocktails alone (Muraoka et al., 2014).
Cellular reprogramming with small molecules alone can also trigger genetic instability and the genetic integrity of the reprogrammed cells might get affected[61].
GMT reprogramming with both inhibitors produces 30% αMHC-GFP reporter expression, while only one inhibitor produces 15% and no inhibitors produces only 4% (Mohamed et al., 2016).
GHMT reprogramming with Akt1 activation and Notch inhibition generated up to 70% conversion efficiency with 45% of the reprogrammed iCMs exhibiting spontaneous beating (Abad et al., 2017).
In the current study we evaluated the potential of keratocytes to produce collagen type II via phenotypic reprogramming with exogenous chondrogenic factors.
