Sentence examples for reprogramming mechanisms from inspiring English sources

The MYC-TAD-OCT4 fusion proteins we generated will be valuable tools for studying the reprogramming mechanisms and for efficient iPSC generation for humans as well as for other species.

Future more selective choice of miRNAs in combination with miR-302 a/d may be utilized to fractionate hiPSC from partially reprogrammed cells based upon their expression profile of fluorescence and to further investigate reprogramming mechanisms.

Differentiation is a highly regulated process and specific reprogramming mechanisms could result in similar epigenetic changes at functionally related genes.

The fact that cell fate is controlled by a series of master transcription factors (OSKM) overwhelms demonstration of reprogramming mechanisms.

In this review, instead of discussing the reprogramming mechanisms, we focus on the promises and challenges of using iPSCs therapeutically.

This study indicates that cell fate decisions can be dictated by manipulating intrinsic signal pathways, and represents an innovative breakthrough in the understanding of reprogramming mechanisms.

Major directions in this field are focused on understanding the reprogramming mechanism, optimizing reprogramming methods to improve iPS cell (iPSC) quality, and applications of the cells for regenerative medicine.

DNA methylation, an important epigenetic reprogramming mechanism, is essential for normal embryonic development.

This process involves a reprogramming mechanism using epigenetic and probably genetic tools (Telerman and Amson 2009).

The current standard strategy by ectopic factor overexpression however has intrinsic limitations in studying the reprogramming mechanism.

Therefore, understanding how early embryos activate Oct4 expression is key in clarifying the oocyte reprogramming mechanism.