Sentence examples for reprogramming due to from inspiring English sources

Non-mobilized peripheral blood is perhaps the ideal cell source for reprogramming due to the ease of obtaining patient samples [7].

T-cells are well suited as a starting material for reprogramming due to their abundance in whole blood (∼6.5×105 3.1×106/ml in healthy adults) [12] and ease of culture using well-established protocols [13], [14].

Secondly, the TLR/NF- κB pathway can switch the phenotype reprogramming due to a change in the NF- κB subunit composition.

These loci, including the stem-cell maintenance genes Sall1, Sall4, and Utf1 as well as validated Klf4 and Oct4 target genes, fail to reactivate during reprogramming due to loss of Utx.

Though transcriptional changes due to the phagocytic uptake process per se – known to occur mostly within the first 2 hours post particle addition – cannot be completely excluded, the MΦ transcript modulation – detected at 24 h post the amastigote addition – very likely reflects MΦ reprogramming due to the presence of cell cycling amastigotes within giant PV.

It has been demonstrated that critically ill injured adult patients, such as burn, trauma, or cardiac surgery patients, experience susceptibility to sepsis because of innate and adaptive immune reprogramming due to the insult [17, 18].

As such, primary granulocytes, monocytes and B lymphocytes are among the most difficult cells to be reprogrammed due to the lack of reliable protocols to expand these cells.

In any case, we omitted c-MYC from the reprogramming cocktail due to the possibility of its interaction with LRRK2 in the context of eukaryotic initiation factor 4E (eIfunctionction regulation (Imai et al, 2008; Ruggero et al, 2004).

This implies that visible iPSC colonies, which can be used for aggregation experiments to analyze ICM contribution, contain substantial numbers of improperly reprogrammed cells due to higher proliferation potential than properly reprogrammed cells.

p53, an essential tumor suppressor gene, plays a well-documented role in the reprogramming process due to its ability to counteract reprogramming [11], [29]– [32].

This reprogramming was due to the direct occupancy of proneural genes by the SYT-SSX2 nuclear complex.