There were significant overall group differences in the Trail Making Test B, the WMS-R Visual Reproduction test, the WAIS Digit Symbol test, and the composite z score (p's ≤ 0.040; Table 3).
Post hoc analysis revealed that the obese group had significantly lower scores on the Trail Making Test B, the WMS-R Visual Reproduction test, the WAIS Digit Symbol test, and the composite z score compared with the normal weight group (p's ≤ 0.004).
Some of these procedures (the Daphnia magna reproduction test) may also be used as screening tests for reproductive toxicity [87 90].
Figure 1 Number of offspring per control vessel in the reproduction test with E. andrei.
Testing was based on the standard collembolan reproduction test (OECD-Guideline 232), following an ECX design.
In this paper, we focused on the 21 day Daphnia magna reproduction test.
The earthworm reproduction test with Eisenia fetida[21] permits the use of Eisenia fetida or Eisenia andrei as test organisms.
In the earthworm reproduction test, there was no significant difference between earthworms exposed to spiked soil and spiked food.
The reproduction test results are presented in Table 1 (NM-101), Table 2 (NM-103), and Table 3 (NM-105).
This study describes the validation of the Potamopyrgus antipodarum reproduction test within the OECD Conceptual Framework for Endocrine Disrupters Testing and Assessment.
