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The new method of assessing the accuracy of the measurement system – R&R (Repeatability and Reproducibility) assessment method is introduced here.
Ca2+off/Ca2+on protocols repeated twice allowed paired comparison between two similar (for reproducibility assessment) or distinct perfusion conditions.
The same conclusion could be taken when the reproducibility assessment was repeated for the 40-components analysis (data not shown).
Ransohoff, et al. [16] emphasized that over-fitting should be explicitly ruled out by reproducibility assessment early on, otherwise further research (that is, additional steps in the validation process) would be unwarranted and wasteful.
These CV values are in line with reproducibility assessment in the SELDI literature [ 17, 18].
Out of 6740 representative associations, 1296 were statistically significant and remained for further reproducibility assessment.
Similar(43)
Reproducibility assessments and standardisation of the acquisition and data analysis methods are crucial when imaging biomarkers are used in multicentre trials for assessing response to treatment.
The between-examiner reproducibility assessments showed a trend similar to the intrasession repeatability assessments.
In order to quantitatively characterize the quality of gene expression calls from both RNA-Seq and microarray, we performed these and other global reproducibility assessments tailored specifically to our experimental design.
In reproducibility assessments conducted in a randomly selected set of 52 images, we calculated a kappa statistic of 0.97 for the left-side images and 0.89 for the right-side images.
This includes defining metrics for reproducibility and assessment of the sensitivity, specificity, resolution and precision with which aspects of the 4D nucleome can be measured.
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