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The recent study by Alfa and Howie [ 30] modelling build-up biofilm as well as the one by Vickery et al [ 31] using endoscope tubing both confirm that repeated rounds of exposure to organic material, cleaning and HLD (complete reprocessing) result in an accumulation of material within the channel.
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The second pathway to proliferation, reprocessing, results in the separation of plutonium from the highly radioactive spent fuel.
Open image in new window Fig. 10 Reprocessed results from Poisson and Marguicchi [28].
Survival of the reprocessing stage may result if the HLD concentration is inadequate (e.g. dilution of HLD), if cleaning is inadequate or if the scope is contaminated post-processing.
According to these results, reprocessing of raw data has the advantage of dampening the effects of the laboratory factors Layout and Read length and increasing the contribution of tissue type on the variance, although not enough to yield a clustering by tissue type in PCA.
The obtained results suggest that reprocessing causes polymer degradation which is a result of the break in the bonds of poly butadiene.
The impact of log transformation was also investigated for the reprocessed FPKM values, resulting in a similar result as the published values.
The plutonium that results from reprocessing spent fuel can power nuclear reactors — which South Korea insists is its only goal — but can also be used to make atomic bombs, as North Korea has done.
In the light of our results with reprocessing conducted via washer/disinfector, we conclude that this contamination was caused by the described insufficient manual reprocessing and not by recontamination as a consequence of inadequate handling, as postulated by the authors [ 22].
Some limits of this method are the need of reprocessing the images (not immediate result) and the need of a motion tracking algorithm (not simple implementation) to reduce errors of interpretation on the luminal side of the plaque.
Open image in new window Fig. 3 Results reprocessed from Li et al. [21].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com