It is well known that DNA methylation plays a repressive role in gene transcription, both in heterochromatin and in repressed, protein-coding, euchromatin [ 1].
These results suggest a repressive role of the CNOT2 complex for the entire MHC II gene cluster on chromosome 6, as displayed in Fig. 6C.
Most Chileans under 35 years old are too young to remember the brutally repressive role the military played under General Pinochet.
The novel addressed homosexuality, child sexuality, and the repressive role of the family, at the same time as it challenged all the conventional devices of novel writing, portraying the problematic nature of the relation between the fictional and the real.
Despite a repressive role of BAHD1, the molecular mechanism underlying BAHD1 heterochromatin targeting remains largely unexplored.
Washington found itself uncomfortably tied to his increasingly erratic and repressive role.
Consistent with a "repressive" role, BAHD1 binds to CpG-rich P3 promoter region of IGF2 (insulin-like growth factor II) then represses IGF2 and IGF2 antisense transcription via the recruitment of MBD1 and HDAC5 (Bierne, Tham et al. 2009).
But the US tired of his increasingly repressive role internally in Panama, and there were indications he was selling his services to other intelligence bodies, not to mention drug-trafficking organisations.
At the same time, he began to play an increasingly repressive role internally in Panama, especially after the assassination of Hugo Spadafora, a political opponent who was found beheaded in 1985.
"I do think that the [Chinese] state uses its positive regulatory role for its politically repressive role," Lewis said, "but I also think you can't say that positive regulatory role doesn't exist, in some shape or form".
A similar repressive role of NR2E3 was observed with M-opsin promoter activity.
