Sentence examples for repressive pattern from inspiring English sources

- Moreover, it has been reported that modifications in the DNA methylome can alter polycomb binding and repressive pattern.

The absence of a repressive pattern over the elements between core X and the telomere agrees with previous observations that this region is not silenced [ 17].

Although the results are novel and valuable in understanding the epigenetic mechanisms involved in the epigenetic silencing of antifibrotic genes in IPF, little is known about the causes and order of events by which repressive patterns of histone and DNA methylation are established and maintained during the disease development and progression.

Differential expression of the endogenous miRNA processing machinery represents a potential explanation for the repressive patterns of miRNA expression that we observed, as recent reports have highlighted the importance of miRNA processing genes in the regulation of miRNA biogenesis and function (Cheng et al., 2009; Van der Auwera et al., 2010).

The developmental fates of stem and progenitor cells within the nervous system are determined by a complex series of spatial and temporal extracellular cues which induce selective classes of cross-repressive patterning genes and combinatorial transcription factor codes that ultimately lead to cellular functional diversification.

Either way the characteristic repressive chromatin pattern is abolished in the absence of Sir proteins.

Such repressive rule must be prevented.

However, two most recent studies reported that 5-Aza-dC treatment converted the transcriptional repressive histone modifications pattern to transcriptional active marks [20], [21].

Like control iPS cells, Lamin A-RNAi iPS cells exhibited active and repressive histone methylation patterns shown by immunostaining of H3K4me3 and H3K9me3/H3K27me3 (Fig. 5B).

Numerous studies have demonstrated overexpression of JmjD3 in cancer cell lines or tumor biopsies, also associated with increased proliferation or control of anti-apoptotic genes such as Bcl-2 [ 211, 220- 223], or for example aberrant repressive PcG methylation patterns in medulloblastoma [ 224, 225].

The Ergenekon arrests are part of a wider pattern of repressive tactics that have been deployed against Erdoğan's critics.