Sentence examples for repressive manner from inspiring English sources
On the surface, the early Letterman resembled his mentor, the icy superstar Johnny Carson: he was apolitical, he was Midwestern, he had a repressive manner and lanky college-boy looks.
These previous reports also showed that RelA acts in a dominantly transcriptionally repressive manner.
We find that lone Eomesa binding is significantly associated with genes both up- and down-regulated on loss of Eomesa, indicating that Eomesa binding independent of Smad2 is indeed functional and acts in both an active and repressive manner.
Since IGF-I and IGFBP-1 were found to be inversely regulated by Smo knockdown it is tempting to speculate that in the case of IGFBP-1 GLI3 may act in a repressive manner, since GLI binding sites were predicted in the promoter region of the IGFBP-1 gene (Additional file 6: Table S5).
To determine whether ZNF703 was binding in a repressive manner to the regulatory regions interrogated, we assessed binding of the histone acetyl transferase p300 and the histone deacetylase HDAC1 to these regions in the presence or knockdown of ZNF703 (Fig 5D, right panel).
A similarly rigged convention then agreed to all manner of repressive proposals such as reserving a quarter of seats in the national parliament and a third in regional ones for the army.
Groups like CPJ, which work to foster a free press around the world, would not be possible without the bravery of the men and women who strive to expose the truth in all manner of repressive climates.
Functional relevance of these positional distinctions became apparent as studies with yeast and flies revealed that the NE can sequester factors that affect gene transcription in both repressive and, surprisingly, activating manners (Akhtar and Gasser, 2007).
Interestingly, circularized chromosome conformation capture sequencing (4C-seq) shows that poised enhancers already establish physical interactions with their target genes in ESCs in a polycomb repressive complex 2 (PRC2 -dependent manner.
There is, however, some evidence that H3K4 methylation can be repressive of transcription, in a manner that is similar to the repressive function of the histone modification made by Set2, namely H3K36 methylation.
Studies first identifying the bivalent state were performed in ESCs and this state was initially suggested to hold genes in a repressive yet primed or poised manner in order to enable rapid activation upon receipt of developmental cues [ 58, 61].
