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Foucault criticizes previous analyses of power (primarily Marxist and Freudian) for assuming that power is fundamentally repressive, a belief that he terms the "repressive hypothesis" (1978, 17 49).
During a lecture delivered one year later the productive aspects of his account of the prison are given far greater prominence (Foucault, 2009b[1976c]), and by the time of his first book on sexuality in 1976 the repressive hypothesis was under sustained attack (Foucault, 1998[1976a]).
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(Marcus has argued, for example, that hermeneuts obsessed with repressive hypotheses have neglected the relationships between women in "Great Expectations").
This suggests that the lack of anthocyanin production in betalain-producing species may be due to a lack of transcriptional activation of all the necessary biosynthetic genes [ 7, 23], although a hypothesis based on repressive interaction between anthocyanin and betalain metabolites and the biosynthetic enzymes has also been suggested [ 24].
Preliminary findings showing that these fusion proteins lead to transcriptional downregulation of AML1 targets, marked by repressive chromatin changes, would support this hypothesis.
These analyses indicate that CR delays the age-related loss of gene silencing, providing strong evidence for the hypothesis that decreases in repressive heterochromatin and loss of gene silencing are a component of the aging process.
Altogether, these results support the hypothesis that permanent repression of CDCA7L in melanoma cells is linked to progressive deposition of repressive epigenetic marks within the gene promoter.
However, contrary to our initial hypothesis, ALI-induced changes in repressive epigenetic histone modifications at these genetic loci were relatively minor.
This is consistent with the hypothesis that T-bet is primarily repressive and functions to block a default Th2 program [ 40, 86, 87].
One hypothesis suggests functional compensation by the polycomb repressive complex (PRC 2, as indicated by its colocalisation with macroH2A1 [ 29].
We have examined the hypothesis that hypoxia might mediate this reduction through repressive effects on microRNA biogenesis proteins.
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