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It is possible that the avian-specific gain of proline residues has contributed to enhancement of repressive characteristics or the formation of novel avian-specific motifs.
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This repressive characteristic of nuclear Spry2 was relieved in 16HBE14o- by shRNA knockdown, and stable expression of mutants (C218A; C221A) that do not interact with the VEGF-A promoter HRE region.
Thus, Nkx3.1 acquired a repressive mark characteristic of EZH2 activity in an ERG-dependent manner.
Either way the characteristic repressive chromatin pattern is abolished in the absence of Sir proteins.
At these stages repressive histone markers characteristic for the germline micronucleus, such as H3K27me3, are removed and 'open' chromatin hallmarks such as acetylated histone H3 are introduced de novo.
Consistent with their low expression levels, lamin-bound genes are rich in histone H3K27me3 and poor in histone H3K4me2 marks, two characteristics of repressive chromatin (Pickersgill et al. 2006; Guelen et al. 2008).
Keeping the law hidden, or behind expensive pay walls, is an unfortunate characteristic of repressive and corrupt societies.
This characteristic reconciliates repressive chromatin marks with transcriptional activity and may provide flexibility for the rapid reprogramming that occurs during ESC differentiation.
My feeling is that repressive regimes repress.
We show that the I/O characteristics of the repressive gene circuit regulated by inducer concentration can be effectively predicted by adequate selection of promoter-RBS components from our libraries.
Still others argued for paternalism as a characteristic of all repressive rural societies marked by "ties of obligation for landlords and rituals of subordination for their retainers". By this definition, paternalism was no longer the distinctive attribute of slavery and easily survived its abolition.
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