Sentence examples for repressive activities from inspiring English sources

The CREM locus produces multiple isoforms with either activation or repressive activities depending on exon configuration in the alternative transcripts [46].

This idea is supported further by data demonstrating that Myc assembles into regulatory complexes with both activating and repressive activities [ 81].

Thus it appears that the activating and repressive activities of YB-1 on gene transcription may involve mechanisms that reflect a requirement for different levels of YB-1 oligomerization and/or perhaps different binding partners.

It could be that their primary role is not to ensure transcriptional repression, or that redundant repressive activities exist.

MUC1 has been ascribed activating as well as repressive activities in hypoxia signaling.

Increasing concentrations of Egr2 led to gradual repression of the reporter activity, demonstrating repressive activities of Egr2 upon the miR-17-92 miR-17-92 miR-17-92

Our findings suggest that, for a subset of fast muscle genes such as mylpfa, Pbx proteins are needed to repress the repressive activity of Prdm1a (Fig. 9B), possibly by inhibiting Prdm1a binding or activity at fast muscle gene promoters.

Therefore, we hypothesized that the expression level of REST in undifferentiated NG108 is controlled by the competition between the activating activity of Sp1 and the repressive activity of another Sp factor.

Therefore, ESE-1 could bind to regions I and III with activating effect and region IV with repressive activity.

Further, the production of both Gli activators and repressors is affected in the absence of the cilium, leading to a loss of Gli repressive activity without a corresponding gain of transcriptional activation [10], [12], [13].

Upon loss of Hairy's repressive activity, bnl expression expands in the muscle cells and abnormally activates the bnl/btl signaling pathway, such that extra TCs become specified.