Sentence examples for repression the function of from inspiring English sources

However, whereas methylation of promoter sequences can lead to transcriptional repression, the function of gene body methylation remains elusive.

Although the function of DNA methylation in gene promoter regions is well established in transcriptional repression, the function of the evolutionarily conserved widespread distribution of DNA methylation in gene body regions remains incompletely understood.

These findings suggested that the overexpression of miR-223 correlates with the poor prognosis of ESCC, possibly because of repression of the function of the FBXW7 protein.

Our present study indicates that high expression of miR-223 had a significant adverse impact on the survival of ESCC patients through repression of the function of FBXW7.

In conclusion, the present study at first indicates that a high expression level of miR-223 had a significant adverse impact on the survival of ESCC patients through repression of the function of FBXW7.

Although it has been clear that piRNAs play a role in repression of retrotransposons during spermatogenesis, the function of miRNA in mouse germ cells has been unclear.

What might be the function of translational repression during mitosis?

To study the function of translational repression in mitosis, we focused on Emi1, a highly repressed gene identified in our ribosome profiling dataset (Supplementary file 3) and translational reporter assay.. First we wished to confirm that regulation of Emi1 expression is due solely to translational regulation, not to changes in Emi1 mRNA expression.

The 1613 mutation can result in the failure of the repression function of the negative regulatory element and in the proliferation of virus-related proteins that might induce hepatocarcinogenesis.

The function of carboxy-terminal repression domain of BRCA1 is not well understood yet, but BRCA1 interacts with several factors through this domain.

Finally, we examined the function of miR-29b-driven repression of CDK6 expression in osteosarcoma cells.