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ICP0 was repressed by liganded TR and this TR-mediated repression required LAT TREs.
The D11.12 element repressed luciferase expression from a reporter construct and full repression required a highly conserved region and YY1 binding sites.
This repression required a functional Myb DNA-binding domain and could not be overcome by fusion to the potent VP16 activation domain.
Thus aa 1-747, retained in our HDAC4ΔC, encompasses all the necessary functional domains, for efficient nuclear import-export and nuclear repression, required for bone development and for overall gross development.
Moreover, importantly, we observed that the introduction of H3K9me1 during repression required DNA replication.
p53-mediated repression required Sp1, because the suppression of all genes tested was halted by Sp1 depletion.
Similar(50)
SMZ is an additional factor repressing FT, and this repression requires the MADS-box transcription factor MADS AFFECTING FLOWERING 1 (MAF1) gene [59].
The policy of all-out repression requires that all significant figures in the black community be pictured as dangerous, violent revolutionaries.
Identification of additional genes whose repression requires ZNF198-like proteins is needed to fully understand their biological functions.
A full understanding of the role of DNA looping in gene repression requires a complete and rigorous analysis of the plethora of data obtained from in-vivo experiments.
To our knowledge, this is the first indication that PcG-mediated repression requires cooperation between several distinct types of PRC1 complex.
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