Sentence examples for repression of protein from inspiring English sources

Zhan, M. et al. Transcriptional repression of protein kinase Cα via Sp1 by wild type p53 is involved in inhibition of multidrug resistance 1 P-glycoprotein phosphorylation.

These miRNAs can bind complementary to messenger RNA (mRNA) and lead to a repression of protein synthesis through degradation of mRNA or transcription blockade.

The genes encoding protein synthesis-related proteins such as aminoacyl-tRNA synthetase (Os03t0749300, Os05t0150900) translation initiation factor 2 (Os03t0296400) and translation elongation factor EF1B (Os06t0571400) were downregulated, suggesting a repression of protein turnover and recycling of amino acids in roots and shoots.

This results in increased p27 or LATS2 protein levels because DND1 inhibits miRNA-mediated repression of protein expression.

This results in translational repression of protein synthesis and, in some cases, destabilization of messenger RNA [1].

In addition, our results predict a global repression of protein translation within the cell due to the downregulation of multiple translation initiation factors.

MicroRNAs (miRNAs) are a large family of single-stranded non-coding RNAs that direct the post-transcriptional repression of protein-coding genes in metazoans.

Although recent studies demonstrate that repression of proteins is frequently mirrored by decreased transcript levels of miRNA targets [15] [17], examples where translational repression is the major component of silencing have been identified as well [17] [19].

In addition to protecting the genome integrity, H3K9 trimethylation is also important for the transcriptional repression of protein-coding genes.

Overall, these results showed a general repression of proteins involved in the response to generic stress and a return to steady-state levels of those proteins specifically required for defence against pathogens.

We show that the expression of the EIF4EBP3 translational repressor represents a peripheral marker of CDC73 function and propose a model whereby starvation resistance, mediated at least in part by de-repression of protein translation, may contribute to parathyroid malignant transformation.