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Gene regulation – some toxins act as a means of general repression of gene expression while others are more specific.
A proposed model for ddCpf1-mediated repression of gene transcription.
H1 is generally thought to condense chromatin structures, leading to the repression of gene expression44,45.
The early cellular response in FOS+ neurons resulted in both induction and repression of gene expression.
Wu, K., Tian, L., Zhou, C., Brown, D. & Miki, B. Repression of gene expression by Arabidopsis HD2 histone deacetylases.
The toolkit allows efficient sequence-specific activation or repression of gene expression in different organisms (bacteria, yeast, mammalian cells).
ncRNA-based genetic manipulation is a potent gene silencing tool whenever repression of gene(s) is desired.
MicroRNAs (miRNAs) form a large class of non-coding RNAs that function in repression of gene expression in eukaryotes.
Selective repression of gene expression in neuropathic pain by the neuron-restrictive silencing factor/repressor element-1 silencing transcription (NRSF/REST).
We show that the CHR element is not only necessary for repression of gene transcription in \(G_0/G_1\), but also for activation in S, \(G_2\) and M phases.
Conversely, it is also likely that repression of gene expression by individual drugs may have masked drug pool induction events resulting in false negatives.
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